Funder: Substance Abuse & Mental Health Services Administration

Deadline: 04/30/2021

Award Details: The Substance Abuse and Mental Health Services Administration (SAMHSA), Center for Substance Abuse Prevention (CSAP), is accepting applications for fiscal year (FY) 2021 Strategic Prevention Framework for Prescription Drugs (Short Title: SPF Rx) grant program.

The SPF Rx grant program provides an opportunity for states, U.S. territories, (herein referred to as “states”), and Tribal entities that have completed a Strategic Prevention Framework State Incentive Grant (SPF SIG) to target the priority issue of prescription drug misuse or another state-level strategic planning process around prescription drug misuse prevention.

The program is designed to raise awareness about the dangers of sharing medications and work with pharmaceutical and medical communities on the risks of overprescribing to young adults. The SPF Rx program will also raise community awareness and bring prescription drug abuse prevention activities and education to schools, communities, parents, prescribers, and their patients.

In addition, SAMHSA will track reductions in opioid overdoses and the incorporation of Prescription Drug Monitoring Program (PDMP) data into needs assessments and strategic plans as indicators of the program’s success.

Number of Awards: 26 awards, $10,000,000 total funding, funding up to $384,000 per year over 5 years, no cost match required. Proposed budgets cannot exceed $384,000 in total costs (direct and indirect) in any year of the proposed project. Annual continuation awards will depend on the availability of funds, grantee progress in meeting project goals and objectives, timely submission of required data and reports, and compliance with all terms and conditions of award.)

Target Population: The SPF Rx grant program builds upon the expertise and established SPF-based prevention infrastructures of states/tribes to address one of the nation’s top substance abuse prevention priorities, prescription drug misuse among youth ages 12-17 and adults 18 years and older.


Eligibility is limited to states, U.S. territories, and tribal entities that have completed a Strategic Prevention Framework State Incentive Grant (SPF SIG) or a similar state-level strategic plan for the prevention of prescription drug misuse and have a state-run PDMP.

Link to RFP: